AAT Discussion Board

Stem cell therapy: Hope or hype?

HARVARD VERITAS

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Read this within the Manila Times digital edition.

DIABETES, Parkinson's disease, degenerative disc disease, macular degeneration, stroke - what do these have in common? Besides being comparatively debilitating conditions, all of those have been treated with stem cell therapy. Since the first stem cell transplant in 1959, stem cell therapy has been touted as a promising treatment modality with functions in many diseases. Zakrzewski describes stem cells (SCs) as unspecialized cells able to differentiating into numerous cell types and possessing the ability for self-renewal. Specifically, mesenchymal stem cells (MSCs) are being explored within the treatment of prevalent conditions, together with but not restricted to neuropathologies, heart illness, diabetes and orthopedic diseases. These cells sourced from the bone marrow, umbilical cord, fat and even dental pulp have been discovered to be of significant use in regenerative drugs. In recent times, analysis has targeted on the flexibility of stem cells to launch varied soluble components and exosomes, which play a role in tissue regeneration.

It's perplexing how we at the moment are listening to efficient cures to what we consider to be intractable diseases, is not it? As with most new discoveries in the sphere of drugs, all this new information begs the query: Are stem cells hope or hype? Studies on cell therapies completed over the previous decade give us hope for his or her use in treating the aforementioned situations and extra, as they've proven efficacy in treating these diseases and even reversing aging. However, it is important to handle expectations, as stem cell therapy does have its limitations. They aren't and should not be promoted as a universal treatment. Specifically, in genetic circumstances like Trisomy 21 (Down Syndrome) or Hunter syndrome, where the underlying problem is at the genetic degree, cell therapies can not provide the identical hope for therapy.

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